The liver is undoubtedly one of the most important organs in our body as it is responsible for a major share of our body’s metabolism. Furthermore, our liver also helps in refining toxins out of our body. However, constant damage to the liver can lead to cirrhosis, and in advanced stages, patients may need a liver transplant. The following discussion dives into details regarding liver cirrhosis and the scenarios in which you may need a transplant.
Cirrhosis is the end result of various types of liver diseases that generally involve abnormal functioning and changes in the structure of the liver. The liver diseases leading up to cirrhosis tend to damage and kill the liver cells. The subsequent inflammation and repair of damaged liver cells lead to the formation of scar tissue.
In addition, healthy liver cells continue regenerating for replacing the dead liver cells. As a result, the newly-formed liver cells group together and form regenerative nodules in the scar tissue. When the volume of scar tissue increases, the liver gradually loses abilities for performing the normal functions.
Causes for Liver Cirrhosis
Being obese or overweight, consumption of too much alcohol and instances of viral hepatitis are some of the risk factors for cirrhosis of liver. However, the causes for liver damage leading to liver cirrhosis are as follows:
- Increased pressure on the portal vein of the liver
- Hepatitis that causes inflammation in the liver
- Alcoholism resulting in liver damage
- Non-alcoholic fatty liver disease that results in a fat buildup in liver cells
- Primary biliary cirrhosis that occurs due to blockage and inflammation in the bile ducts
- Inherited diseases such as cystic fibrosis, hemochromatosis, Wilson’s disease and autoimmune diseases such as lupus and HIV
Symptoms of Early Stages of Liver Cirrhosis
It is not necessary that early stage liver cirrhosis will display symptoms at first, however, with time, you will notice some signs and symptoms which is the result of damaging effects on the liver. Some of the symptoms of liver cirrhosis are as follows:
- Loss of appetite
- Loss of muscle mass
- Weight Loss
- Loss of brain function
- Yellowing of skin and eyes
- Darkening of the urine color
- Swelling and pain in the abdomen
- Swelling and pain in the legs
- Excessive itching
- Kidney failure
- Easy bruising
Instances when Liver Transplant are Necessary
Liver transplants are recommended only for patients with end-stage liver disease or advanced liver cirrhosis. The medical team considers many factors before recommending a liver transplant such as,
- The severity of the patient’s condition
- The mental and physical well-being of the patient
- Medical history of the patient
- History of chronic infections such as tuberculosis
- Level of support from family and friends
The medical team also checks the Model of End-Stage Liver Disease (MELD) score to rank the degree or severity of the liver disease to determine whether liver transplant is to be done immediately or can be delayed.. The higher the number, the more critical the case is. MELD Score for end-stage liver disease is based on values of creatinine, bilirubin and international normalized ratio for prothrombin time (INR). The creatinine levels indicate the health of kidneys, and the international normalized ratio indicates the capability of your liver to make blood-clotting proteins.
Simpler and Cost-Effective Options for Liver Transplants
Different approaches for liver transplant in India are available at cost-effective prices for people from various corners of the world. People from all corners of the world can avail a different and cost-effective approach for liver transplant in India. The exceptional liver transplant success rate in India makes it favorable to opt for a living-donor liver transplant (LDLT). The liver transplant surgeons in India are adept and have skilled experience in performing procedures that not only give the patient a new life, but also provides the donor better recovery with no lifelong complications. And thanks to the regenerative capabilities of the liver, the donor can regain full liver functionality in a short span of time. The best liver transplant hospitals in India are equipped with the best infrastructure and also have a multi-disciplinary team of doctors, surgeons, specialists and medical staff that ensures 360-degree care of the donor and the patient.
Criteria for Eligibility of Donors
Every patient who is need of a liver transplant, is primarily put on a cadaver liver transplant list, until there is a living-donor available. The cadaver list is organized based on the severity of the condition of the patient’s condition. However, in some cases, delaying the liver transplantation can be fatal to the patient. LDLT is suggested if there is an availability of donor liver. Generally, the donor is someone related to the patient who willingly offers to donate the organ. The donor volunteers to the transplant process. For a LDLT the safety and well-being of the donor is of the utmost importance. After the initial evaluation of the donor, the procedure is taken forward. However, the donor should not have the following for validating their eligibility.
- Any history of Hepatitis
- Drug addiction
- HIV infection
- Alcoholism or frequent alcohol consumption
- History of cancer
- Psychiatric illness
Safety of the Donor and the Patient
With the help of a competent liver transplant surgeon in India, you can be assured of safely of both the donor and the patient. There are absolutely no complications for the donor or the patient. The donor has to stay in the hospital for up to 10 days or more in certain cases. Generally, the liver regenerates fully in two months.
Patients could have to stay in the hospital for three weeks or more so that the doctors can evaluate their condition. The use of supporting medications such as anti-rejection medicines can help in avoiding any short-term or long-term complications. Furthermore, the minimally invasive procedures help patients and donors resume their active lifestyles without any complications. In addition, you can also receive effective guidance from the medical team regarding home care for the patient.
Don’t Wait Further!
If you are experiencing any symptoms of liver cirrhosis, then contact the best liver transplant hospital in India for cost-effective treatment right now. Don’t miss this opportunity to have a better life